Gen Chen Selected Research

Caspase 3 (Caspase-3)

1/2019

Metformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy via the Hedgehog pathway.

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Gen Chen Research Topics

Disease

8	Neoplasms (Cancer) 03/2024 - 05/2014
5	Cardiomegaly (Heart Hypertrophy) 06/2023 - 01/2019
4	Hyperglycemia 01/2021 - 10/2018
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 01/2016
3	Fibrosis (Cirrhosis) 04/2023 - 01/2019
3	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 01/2021
3	Inflammation (Inflammations) 01/2022 - 01/2021
2	Liver Neoplasms (Liver Cancer) 03/2024 - 09/2010
2	Hepatocellular Carcinoma (Hepatoma) 03/2024 - 11/2019
2	Liver Cirrhosis (Hepatic Cirrhosis) 07/2023 - 01/2022
2	Alveolar echinococcosis 01/2022 - 10/2006
2	Neoplasm Metastasis (Metastasis) 05/2021 - 11/2019
2	Hyperlipidemias (Hyperlipidemia) 01/2021 - 01/2021
2	Hypertension (High Blood Pressure) 09/2019 - 01/2019
1	Sarcopenia 03/2024
1	Hepatitis B 03/2024
1	Reperfusion Injury 02/2024
1	Infections 10/2023
1	Necrosis 10/2023
1	COVID-19 10/2023
1	Thrombosis (Thrombus) 10/2023
1	Respiratory Tract Infections (Respiratory Tract Infection) 10/2023
1	Rectal Neoplasms (Rectal Cancer) 06/2023
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 04/2023
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 10/2022
1	Infarction (Infarctions) 05/2022
1	Aneuploidy (Aneuploid) 01/2022
1	Genomic Instability 01/2022
1	Papillary Thyroid Cancer 06/2021
1	Wounds and Injuries (Trauma) 06/2021
1	Non-alcoholic Fatty Liver Disease 01/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Type 2 Diabetes Mellitus (MODY) 01/2021
1	Fatty Liver 01/2021
1	Hypercholesterolemia 01/2021
1	Insulin Resistance 01/2021
1	Obesity 01/2021
1	Overweight 01/2021
1	Heart Failure 10/2020
1	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 04/2020

Drug/Important Bio-Agent (IBA)

4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 05/2015
4	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020 - 01/2016
3	Biomarkers (Surrogate Marker)IBA 02/2024 - 01/2021
3	Sirtuin 1IBA 01/2022 - 01/2019
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2010
2	fibroblast growth factor 13IBA 06/2023 - 10/2020
2	Glucose (Dextrose)FDA LinkGeneric 06/2021 - 01/2019
2	Circular RNAIBA 06/2021 - 11/2019
2	CateninsIBA 05/2021 - 01/2021
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2021 - 01/2021
2	MicroRNAs (MicroRNA)IBA 11/2019 - 05/2014
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 01/2019
2	Transforming Growth Factor beta (TGF-beta)IBA 08/2015 - 10/2006
1	DNA (Deoxyribonucleic Acid)IBA 03/2024
1	alpha-Fetoproteins (alpha-Fetoprotein)IBA 03/2024
1	AnticoagulantsIBA 10/2023
1	CollagenIBA 07/2023
1	Recombinant ProteinsIBA 07/2023
1	Protons (Proton)IBA 06/2023
1	AmidesIBA 06/2023
1	APTIBA 06/2023
1	Glucagon (Glukagon)FDA Link 04/2023
1	RNA (Ribonucleic Acid)IBA 04/2023
1	Insulin (Novolin)FDA Link 04/2023
1	apalutamideIBA 01/2023
1	fibroblast growth factor 18IBA 01/2023
1	AndrogensIBA 01/2023
1	NADPH Oxidase 4IBA 01/2023
1	ParaquatIBA 10/2022
1	human FGF6 proteinIBA 05/2022
1	AntigensIBA 01/2022
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2022
1	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 01/2022
1	EnzymesIBA 01/2022
1	protein kinase C lambdaIBA 06/2021
1	BromidesIBA 06/2021
1	Lactic Acid (Lactate)FDA LinkGeneric 06/2021
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 06/2021
1	Competitive Endogenous RNAIBA 06/2021
1	Epidermal Growth Factor (EGF)IBA 05/2021
1	morinIBA 01/2021
1	sophoricosideIBA 01/2021
1	histone deacetylase 3IBA 01/2021
1	Liver X ReceptorsIBA 01/2021
1	LipidsIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA 01/2021
1	Transcription Factor RelAIBA 01/2021
1	clazosentanIBA 04/2020
1	Cilostazol (Pletal)FDA LinkGeneric 04/2020
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2020
1	p38 Mitogen-Activated Protein KinasesIBA 01/2020
1	Mechanistic Target of Rapamycin Complex 2IBA 10/2019
1	MetallothioneinIBA 10/2019

Therapy/Procedure

5	Therapeutics 10/2023 - 12/2018
1	Hepatectomy 03/2024
1	Kidney Transplantation 10/2023
1	Aftercare (After-Treatment) 10/2023
1	Prostatectomy (Retropubic Prostatectomy) 01/2023
1	Neoadjuvant Therapy 01/2023